The Black Stars have arrived in Libya ahead of the return leg qualifier against Sudan Tuesday.
The Ghanaian players left Accra on Sunday following a recovery training at the Accra Sports Stadium a day earlier.
The entire team left the Kotoka International Airport for the Libyan city of Benghazi, where the match will be played.
Ghana were held to a goalless draw by Sudan in the first leg, putting the four-time African champions at risk of missing out.
Therefore, the game against Sudan is a must-win for the Stars.
They currently lie third in Group F behind Angola, on maximum nine points, and Sudan, on four points.
There will be a scheduled pre-match press conference on Monday for both Ghana coac Otto Addo and Sudan James Kwesi Appiah.
Tuesday’s game will be played at the Martyrs of February Stadium at 1300GMT.